How to Use the Monarch Initiative ChatGPT Plugin?

1. How to install the Monarch Initiative ChatGPT Plugin?

Installation Steps:

1. Open the ChatGPT website.
2. Log in to your ChatGPT account.
3. Make sure you have enabled the ChatGPT plugin in your account.
4. Select the GPT-4 model.
5. Select the Plugins.
6. Click on the dropdown arrow to open the list of installed plugins and scroll down to the bottom to click on "Plugin Store".
7. Find Monarch Initiative in the plugin store and click on "Install".

2. How to use the Monarch Initiative ChatGPT Plugin?

Usage Steps:

1. Enable the Monarch Initiative plugin.
2. In the ChatGPT chat box, enter the keywords or questions you want to query, for example, "Find diseases related to genetics."
3. ChatGPT will use the Monarch Initiative plugin to provide you with relevant biomedical data.
4. Based on the returned results, you can continue asking questions or perform deeper queries.

3. A few examples of prompt words for using the Monarch Initiative ChatGPT Plugin

• "List genes related to leukemia." (Triggers disease-related gene list functionality)
• "Search for phenotype XYZ." (Triggers phenotype search functionality)
• "Which diseases are associated with gene XYZ?" (Triggers gene-associated diseases list functionality)
• "Which phenotypes are related to disease XYZ?" (Triggers disease-related phenotypes list functionality)
• "Find variants of gene XYZ." (Triggers gene variant search functionality)

4. What are the advantages and disadvantages of the Monarch Initiative ChatGPT Plugin?

Advantages:

• Provides a comprehensive platform for biomedical information.
• User-friendly and easy to use.
• Cross-species gene, genotype, variant, disease, and phenotype data.

Disadvantages:

• Users without a background in biomedical fields may need some time to familiarize themselves with and understand the returned results.

5. Are there any restrictions on using the Monarch Initiative ChatGPT Plugin?

The main limitation of using the Monarch Initiative ChatGPT plugin is that it primarily focuses on biomedical data. Additionally, it may not encompass all biomedical data but represents a representative subset.

6. What are some tips for using the Monarch Initiative ChatGPT Plugin?

• Use clear and specific prompts to obtain more accurate results.
• If unsure about a term's meaning, perform a general search first and then use the plugin for more in-depth queries.

7. What are the consequences of improper use of the Monarch Initiative ChatGPT Plugin?

Improper use of the Monarch Initiative ChatGPT plugin could lead to misunderstandings or misuse of biomedical data, potentially resulting in adverse effects on research or clinical decisions.

8. Conclusion

The Monarch Initiative ChatGPT plugin is a powerful tool that allows users to search and retrieve basic information about genes, diseases, and phenotypes from the Monarch Initiative knowledge graph. By using clear and specific prompts, users can easily obtain relevant information about genes, diseases, and phenotypes.